Healthcare and Life Science Market Research

Tuesday, June 23, 2020

Amplification Sda Market Manufacturing Index Study during forecast period 2019 - 2029

Strand Displacement Amplification (SDA) allows in-vitro nucleic acid amplification using isothermal technique. Nucleic acids being the encoding information in all living forms, used in detecting hereditary diseases, cancers and pathogens. Isothermal strand displacement amplification is a method alternative to PCR-based nucleic acid amplification. PCR requires separate thermocycling apparatus whereas, strand displacement amplification allows 10(10)-fold amplification of a target DNA sequence without the use of external apparatus, making it robust and cost effective. Strand displacement amplification was the first amplification technology to be coupled with real-time homogeneous fluorescence-based detection for detecting various clinical conditions. Thus, strand displacement amplification technique overcomes disadvantages of PCR. Isothermal strand displacement polymerase reaction (ISDPR) an advanced form of strand displacement amplification, is being widely used having more detection platforms.

Strand Displacement Amplification (SDA) market; Drivers and restraints

Increasing cases of infectious diseases is one of the major cause of deaths. Tuberculosis, syphilis, malaria, pneumonia are most prevalent diseases. These conditions keeping its prevalence in current scenario also due to poor or late diagnosis. The Rapid amplification technique like strand displacement amplification technique without the use of thermocycling process, the technique is being opted by most of the countries. Strand displacement amplification technique provides more significant results compared to culturing in cases of bacteremia due to early detection of organisms, thus increasing the demand of strand displacement amplification technique.

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Moreover smear based diagnosis where results can be missed due to low levels of bacteria, strand displacement amplification technique is useful in making the diagnosis more sensitive leading the growth of strand displacement amplification market. Strand displacement amplification technique is emerging in agriculture and forensic, helping in the wide spread use of strand displacement amplification technique. The multiple strand displacement amplification technique is also being evaluated in various developed countries which can provide results more efficiently. The strand displacement amplification technique require sample preparation, also cannot amplify long nucleotide sequences making it less efficient there by hampering the growth of strand displacement amplification market. The results by strand displacement amplification technique can sometimes show false positive results which can be the major reason which can decline the use of strand displacement amplification technique. Also lack of skilled professionals can majorly restrict the demand for Strand displacement amplification market.

Strand Displacement Amplification (SDA) market: Segmentation

Global strand displacement amplification market is segmented based on application, end user and region

Based on application, strand displacement amplification market is divided into following;

Tuberculosis
Hepatitis
Pneumonia
Malaria
Cancer

Based on end user, strand displacement amplification market is divided into following;

Research institutes
Hospitals
Diagnostic laboratories

Strand Displacement Amplification (SDA) market: Overview

The market for tuberculosis diagnosis is highly valued making it most rapid diagnosis due to sensitive results, rising health awareness are the factors responsible to increase the growth of strand displacement amplification market over forecast period. Based on end user the global strand displacement amplification market will be dominated by diagnostic laboratories over the coming year as nucleic acid amplification has many values in the healthcare sector. Also, strand displacement amplification technique is used by research laboratories, majorly in the forensic labs, lead the growth of strand displacement amplification market.

Strand Displacement Amplification (SDA) market: Regional overview

Globally the Strand displacement amplification market especially includes in North America, Europe and Asia-Pacific, South America, and Africa. North America holds the maximum share in Strand displacement amplification market globally. Strand displacement amplification market will experience rapid growth during the forecast period in APAC. Due to emergence of new small players ultimately increasing the growth of Strand displacement amplification market in Middle East and Africa.

Strand Displacement Amplification (SDA) market; Key players

Some of the profiled key players in Strand displacement amplificationt market that are prevalent globally include New England Biolabs, Hopax Fine Chemicals, Nippon Genetics .Co .Ltd, G Biosciences, BioRad. Proteon Pharmaceuticals, usually deals with the manufacturing of polymerase enzyme manufacturing used in Strand displacement amplification market.

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Cdna Reverse Transcription Kit Market Adoptability Implications and Growth Prospects during forecast period 2019 - 2029

Synthesis of DNA from RNA through reverse transcription results in the production of complementary DNA (cDNA). The first strand cDNA is referred to the cDNA formed through reverse transcription of RNA using reverse transcriptases and primer complementary to the 3’ end of the RNA. This first strand cDNA is then used as a template for PCR amplification of the cDNA as well as for synthesis of double stranded DNA. Reverse transcription PCR (RT-PCR) is commonly combined with real time PCR (qPCR) and is known as qRT-PCR.

cDNA reverse transcription kits are kits that contain all required mixes of reagents and enzymes required for the synthesis of cDNA and PCR amplification. Based on application there are a number of kits available in the market. Some of the applications include, library construction, small RNA cloning, subtractive hybridization, gene cloning, and florescent probe applications.

Some of the key factor that are driving the growth of the cDNA reverse transcription kit market include, rise in R&D spending and activities, increase in biotechnology companies worldwide, increase in PCR applications, and increase in demand for easy and ready to use kit based DNA and RNA products. However, some factors such as insufficient skilled professionals and cost of kits and associated equipments like PCR, may hamper the adoption of the cDNA reverse transcription kits and thereby restrict the market growth.

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Many players in the market are focused towards including High Capacity cDNA Reverse Transcription Kits. These kits are focused on generating high yield and better precision than other cDNA synthesis kits. Another factor that these kits offer is significantly low price of the kit when compared to other standard cDNA synthesis kits. Such developments will offer lucrative growth opportunity for players in the cDNA reverse transcription kits market.

Based on application, the global cDNA Reverse Transcription Kit market is segmented into:

Florescent Probe Application
Library Construction
One-Step RT-PCR
RACE
Small RNA cloning
Standard RT-PCR
Subtractive Hybridization
Two-step RT-PCR

Based on end user, the global cDNA Reverse Transcription Kit market is segmented into:

Biopharmaceutical companies
Biotechnology Companies
Academic & Research Institutes

The market is segmented based on applications and end users. While cDNA reverse transcription kits have a number of applications, library construction, RACE and cloning are the most common application. These kits have a significant adoption in the biopharmaceutical and biotechnology industry. However, academic and research institutes also offer significant revenue contribution to the cDNA reverse transcription kits market.

With Increasing R&D spending in North America, the market for cDNA reverse transcription kits is rising and holds a significant share of the market. Europe is expected to be the next most lucrative region followed by Asia Pacific for investments in cDNA reverse transcription kits market. Asia Pacific region is expected to have a significantly high growth rate owing to the rising R&D activities in countries like Japan, China, India and Australia.

Some of the key players in the market include, ThermoFisher Scientific, Takara Bio Inc., Bio-Rad Laboratories, Inc., Merck KGaA, Enzo Life Sciences, Inc., Sisco Research Laboratories Pvt. Ltd., Solis Biodyne, New England Biolabs. Most key players are focused on expansion of distribution channels to ensure better geographical reach of their products. While some companies are working towards developing unique kits that meet the demands of high yield products, other companies are expanding their product portfolio through acquisition of companies offering cDNA reverse transcription kits among others.

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Batten Disease Treatment Market Manufacturing Trend Analysis during forecast period 2019 - 2029

Batten Disease is a genetic disorder which is caused by autosomal recessive genetic mutation mainly occur in the childhood. Batten disease is also considered as lysosome shortage disease. Symptom of batten diseases occur due to malfunctioning of the body and can be observed between the age of five and fifteen years but it takes a few years to show symptoms such as vision loss, behaviors changes resulting in blindness and Parkinson-like symptoms. FDA approve first cerliponase alfa first ever drug to treat a slow loss of walking ability. Till, there is no treatment but there are few tests for batten disease and can be diagnosed by some laboratory tests which include blood test, urine sample MRI and CT scan. According to the National Human Genome Research Institute (NHGRI), Juvenile batten is one of the common diseases affecting almost 30 million population. There are some clinical trials studies being carried out in the North America, Western Europe, and Asia Pacific which is expected to increase the demand for batten disease treatment.

Increased prevalence of disease and clinical trials are expected to spur the growth of batten disease treatment market. A number of physical therapies may be used to treat the batten disease such as stem-cell therapy, enzyme-replacement therapy and gene therapy are expected to increase the demand for batten disease treatment. In addition, there is also fetal stem cell material which may be possible to treat brain of affected children and this is anticipated to increase the growth of batten disease treatment market. Besides, receiving vitamin supplements also help affected children and resulted slowing of the batten disease which is expected to increase the growth of batten disease treatment market.

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However, factors such as no specific treatment for batten disease treatment will hinder the growth of batten disease treatment market.

The global Batten Disease Treatment market is segmented on the basis of Disease type, Treatment and Geography:

Based on Disease type, Batten Disease Treatment Market is segmented into the following:

Juvenile NCL
Infantile NCL
Late infantile NCL
Adult NCL

Based on Treatment type, Batten Disease Treatment Market is segmented into the following:

Occupational Therapies
Physical Therapies

Batten disease treatment market is segmented into disease type and treatment type. As yet there is no specific treatment for batten disease but seizures can be reduced with anticonvulsant drugs, and also controlled by certain therapies to reduces medical problem. On the basis of disease type, Juvenile NCL is expected to increase the demand for batten disease treatment market. Juvenile NCL is a common disease which occur affect almost 1 out every 10 American. On the basis of treatment type, batten disease treatment is segmented into occupational therapies and physical therapies. For patients, these therapies are used to retain their functions but not prohibited the final result of the disease.

Geographically, the batten disease treatment market is segmented into regions such as Latin America, Europe, North America, South Asia, East Asia Middle East & Africa and Oceania. North America is projected to emerge as prominent market in the global Batten Disease treatment market due to increasing incidence of batten disease, increasing healthcare expenditure and presence of local manufactures. Further, Europe is the second regional market after north America which is expected t show significant growth in coming years. The growth is due to local manufactures and increased prevalence of batten disease. However, Asia-Pacific is expected to witness minimum growth due to lack of awareness among the manufactures and patient pool.

Some of the major key players competing in the global batten disease treatment market are Seneb BioSciences, Inc., ReGenX Biosciences LLC, BioMarin Pharmaceuticals, Ionis Pharmaceuticals, Inc., and Celenex and Inc. Manufacturers are participating for the development of effective and new drugs for the treatment of batten disease are expected to surge the growth of batten disease treatment market.

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Cutaneum Treatment Market Movement & Profitability Analysis during forecast period 2019 - 2029

Cornu cutaneum is an adequately undynamic projectile, asymmetrical, hyperkeratosis bump. It is a typical type of non-melanoma skin cancer. Although 60% of the cutaneous horns are not harmful in nature, the probability of skin cancer is going to occur. Excisional biopsy is adequate for treatment of the lesion which is present overhead and face. But if cornu cutaneum is enclosed of sensitive cosmetic areas then Electro cauterization, laser ablation, and cryotherapy are new develop technologies establish in the cornu cutaneum treatment market. According to the annual report American cancer society, it is estimated that in 2020, 100,350 new cases, of skin cancer will be diagnosed in the US and 6,850 people will die in the US. While from 100,350 there are 60,190 are male and 40,160 female will be diagnosed by cornu cutaneum treatment. Also According to the American cancer society, the overall incidence of melanoma skin cancer rise rapidly over the past 30 years, but trends in the past decade vary by age. Started from 2007 till 2016, the percentage decreased by 1.2% per year in individuals younger than 50 years of age while increasing by 2.2% per year amongst ages 50 and older.

Accessibility of progressive healthcare facilities, flourishing structured regulatory framework, advanced disposable income and reimbursement coverage are the factors which will boost up the growth of the cornu cutaneum treatment market. As well as a high degree of understanding about Cornu cutaneum treatment will escalate the growth of the cornu cutaneum treatment market in well-developed countries. Related variance category of cornu cutaneum treatment and the growing number of cases of cornu cutaneum are some of the factors that will propel the growth of the cornu cutaneum treatment market.

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The global market for cornu cutaneum treatment is divided based on segmentation by product types, distribution channel and geography:

Segmentation by Product Type
- Drugs
  - 5-Fluorouracil
  - Vismodegib
  - Sonidegib
  - Vismodegib
- Laser Devices
  - Excimer Lasers
  - Nd:YAG Laser
  - CO2 Laser
  - Diode Laser
Segmentation by Distribution Channel
- Retail Sales
  - Retail Pharmacy
  - Drugstore
  - E-commerce
- Institutional Sales
  - Hospitals
  - Specialty Clinics

Among product type of 5-Fluorouracil drug, the type is expected to dominate the global cornu cutaneum treatment market. As in the view of the fact, 5-Fluorouracil drug is most commonly recommended cornu cutaneum treatment for patients. Also, vast R&D activities and developing treatment is fueling the growth of the cornu cutaneum treatment market. Cornu cutaneum is an utmost frequent disorder in the globe. Moreover that there is a great escalation in the rate of cornu cutaneum treatment.

Advanced healthcare facilities, improved medications and advancement in research and development will propel the growth of the North America Cornu cutaneum treatment market. Europe also is shown to have tremendous growth in the cornu cutaneum treatment market due to increasing demand and acceptance of new therapeutics and seeking better treatment options in the region. The Asia Pacific has a significant contribution to the Cornu cutaneum treatment market, because of the rising prevalence of Cornu Cutaneum treatment and growing awareness among people for early diagnosis in cornu cutaneum treatment. India, China, and South Africa are likely to show significant growth in the Cornu cutaneum treatment market due to the increased focus of government to improve the healthcare facilities. Developing event in cornu cutaneum treatment signalling that increase in global warming. Also, it’s predicted that ultraviolet radiation (UV) is the producer of cornu cutaneum in the 90% of cases.

Some of the key players present in global cornu cutaneum treatment market are F. Hoffmann-La Roche AG, Pfizer Inc., Teva Pharmaceutical Industries Ltd., Meda Ab, Sun Pharmaceutical Industries Ltd., GlaxoSmithKline plc. Vidac Pharma, Bausch Health Companies Inc., ImClone Systems Incorporated, Sanofi SA, Ushio, Inc., Hetero Pharmaceuticals, Merck & Co., Inc., Cipla Limited etc. among others.

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Capsule Endoscopy Belts Market Deployment Pattern Scenario during forecast period 2019 - 2029

Capsule Endoscopy belts Examination is a Diagnostic procedure that consist of small wireless camera embedded in a vitamin-size capsule that take pictures of digestive tract. Capsule endoscopy belts was developed in mid 1990s, and has received FDA approval for use on 2001, and was FDA approved a first line small intestinal imaging device in 2003. These capsules are very small, easy to swallow, painless and disposable in characteristics. Capsule endoscopy belts device is used to diagnose the Gastrointestinal related disorders such as GI bleeding, bowel diseases, stomach cancer and ciliac disease amongst other aapplications. The capsule travel through the digestive tract from esophagus to small intestine, the camera takes thousands of pictures in all over the areas of GI system during the procedure. These pictures are transmitted to a data recorder which is implanted on a belt. The capsule endoscopy camera take 50,000 to 60,000 digital images in 8-9 hours. The procedure take 8-12 hours but the patient can go perform there routine task during the study. The capsule endoscopy belt includes wireless capsule, work station, sensor and data recorder. The data recording system is device that will be worn around the patient’s waist so that the images captured by the capsule will transmit easily to the data recording system.

The elderly population is highly prone to gastrointestinal diseases including certain types of cancers. The capsule endoscopy belts devices plays an integral role in early diagnosis and in the treatment of these diseases, along with innovative imaging technologies and new component innovations. Rise in number of chronic gastrointestinal diseases such cancer, GI bleeding in developed as well as developing countries are expected to be the major driver of capsule endoscopy belts market over the forecast period.

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Moreover, favorable reimbursement scenario in some developed region along with adoption of people towards technology enabled procedures are some drivers responsible for the growth of capsule endoscopy belts market over the coming years. However, high cost of the procedure and complication such as capsule retention inside the body are some of the factor associated to impede the market growth over the forecast period. Also, poor health care facility and substitutes available in developing economies will also contribute to hamper the market potential over the coming years.

The global capsule endoscopy belts market is segmented on the basis of product type, component type, by application, by end user and by region.

Capsule endoscopy belts market segmentation by product type:

Oesophageal Capsule
Small Bowel Capsule
Colon Capsule

Capsule Endoscopy belts market segmentation by Component type:

Capsule endoscopy Belts System
Workstation and Recorders

Capsule Endoscopy belts market segmentation by Application:

Chron’s Disease
Small bowel Diseases
Obscure Gastrointestinal diseases
Small intestine diseases
Esophageal diseases
Colonic Diseases
Others

Capsule Endoscopy belts market segmentation by end user:

Hospital
Ambulatory Surgical centers
Specialty clinics

The capsule endoscopy belts market is expected to grow exponentially over the forecast period owing to have more number of R&D for technological innovations. The component segment of capsule endoscopy belts market is expected to hold the major market share over the forecast period due to its more number of units sold in the market. According to the study, approximately 141,000 people in United States were diagnosed with GI related cancers and around 49,000 people died in the year 2011 as per the data revealed by American cancer Society. Also, according the Centers for Disease Control and Prevention, around 1.3% of U.S. adults were diagnosed with Crohn’s disease as compared to 0.9% adult patients in the year 1999. Capsule endoscopy belts are widely used for the diagnosis of GI Bleeding considering the fact, the obscure gastrointestinal disease by application is expected to hold the next major share over the forecast period.

Geographically, the global Capsule endoscopy Belts market is segmented into regions such as Latin America, Europe, North America, South Asia, East Asia Middle East & Africa and Oceania. North America is expected to hold the major revenue due to acceptance of technologically enabled devices and due to availability of good healthcare infrastructure. The Europe region will show the next robust growth in terms of revenue share due to their reimbursement policies over the coming years South Asia And East Asia is expected to show a next robust growth due to increasing more number of healthcare facilities in these regions. Middle East and Africa is expected to be the most lucrative regions considering the fact of poor healthcare infrastructure in these region. Considering all the fact, the Capsule endoscopy Belts market is expected to grow exponentially over the forecast period.

Example of some of the market participants of Capsule endoscopy Belts market identifies across the value chain include Medtronic Plc, Olympus Corporation, Stratis Medical Inc., Fujifilm Corporation, IntoMedic Co., Ltd., CapsoVision, RF System Lab, Chongqing Jinshan Science and Technology (Group) Co., Ltd, Given Imaging Ltd. Are some key market player for capsule endoscopy Belts market.

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Anular Closure Devices Market Supply-side Opportunity Assessment during forecast period 2019 - 2029

The increasing number of injuries, accidents and body deformation demand for advance surgeries and treatment. Medical devices industry players are focusing on the introduction of new devices and technologies to provide effective treatment. Knee, spinal and hip injuries are the most common form of the injuries associated with the accident and trauma. The increasing number of lumbar disc herniation and spinal injuries lead to demand for innovative devices such as anular closure devices. Anular closure devices such as Barricaid anular closure device is an implant which has three components mesh (PET layers connected with PTFE-coated PET sutures), anchor and marker. Barricaid anular closure device is made of titanium and it’s attached to a polyester mesh. Barricaid anular closure device is intended to close the hole in patient spinal bone following a limited discectomy procedure in the lower back after an initial herniated disc. Barricaid anular closure devices are intended to implant for discectomy to prevent reherniation and recurrence of pain or dysfunction. Some of the other products available for the annulus fibrosus repair and annulus closure are the Xclose Tissue Repair System, Anchor Band Suturing System, Inclose Surgical Mesh System, and Disc Annular Repair Technology (DART) System.

The increasing number of lumber discectomy procedure expected to propel the growth of the anular closure device market over the forecast period. The increasing number of accidents and injuries expected to favour the growth of the anular closure devices market. Growing ageing population augmented to boost up the demand for the anular closure devices market as high number of lumbar disc herniation cases among older patients. Increasing per capita healthcare expenditure, growing number diagnostic procedure such as MRI scans for spine expected to favours demand for the anular closure devices. Favourable reimbursement policies implementation in the developing and developed countries expected to favour the demand for the anular closure devices. Moreover, side effects and infections risk associated with the anular closure procedures expected hamper the growth of the anular closure devices market.

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The global anular closure devices market is classified on the basis of product type, end user and region.

Based on product type, anular closure devices market is segmented into the following:

Suturing System
Surgical Mesh
Reherniation Reduction Device

Based on end user, anular closure devices market is segmented into the following:

Hospitals
Ambulatory Surgical Centers
Spine Surgery Centers

The increasing number of research and development activities for the introduction of new anular closure devices expected to drive the growth of the anular closure device market over the forecast period. The growing ageing population and the rising number of affordable medical services and procedures in the developed countries are expected to propel the anular closure devices market. Increasing prevalence of the disc degeneration, endplate lesions, annular tears/fissures and spondylolisthesis expected to flourish the demand for the anular closure devices. Increasing integration of minimally invasive imaging technologies for the operative procedures and devices implantation expected to spur the demand for the anular closure devices market.

North America anticipated to represent highest market value share in the global anular closure devices market as high number of lumber discectomy procedures performed in the regions. Europe expected to contribute the second highest market value share in global anular closure devices market as improving reimbursement policies for the spinal surgeries. East Asia and South Asia expected to grow with significant growth rate as the growing prevalence of disc degeneration and spondylolisthesis in the region and highest patient pool in the world. India and China projected to grow with a faster pace as increasing demand for the new technologies and devices for the spinal disorders treatment and growing healthcare expenditure. Middle East Asia likely to show less growth rate as compared to Asian countries as slow developments in the healthcare sector.

Anular closure devices market is a consolidated market with less number of players. Some of the key players across the value chain of anular closure devices market are Intrinsic Therapeutics, Anulex Technologies, Inc., Magellan Spine Technologies, Inc. and others.

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